Post Time: 2025-02-21
Error: No content files found.. Chapters 0:00 Introduction 0:47 How long does it take for Viagra to work? 1:09 How long does Viagra last? 1:29 what is the recommended does for Viagra? 1:54 What are the side effects of Viagra? Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension.[4][8] It is unclear if it is effective for treating sexual dysfunction in women.[8] It is taken by mouth or by injection into a vein.[8] Onset is typically within twenty minutes and lasts for about two hours.[8] Common side effects include headaches, heartburn, and flushed skin.[8] Caution is advised in those with cardiovascular disease.[8] Rare but serious side effects include a prolonged erection (priapism) that can lead to damage to the penis, vision problems, and hearing loss.[8] Sildenafil should not be taken by people on nitrates such as nitroglycerin (glycerin trinitrate), like this as this may result in a serious drop in blood pressure.[8] Sildenafil should not be taken within four hours of taking an alpha blocker. Sildenafil acts by blocking phosphodiesterase 5 (PDE5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis.[8] It requires sexual arousal to work.[8] It also results in dilation of the blood vessels in the lungs.[8] Pfizer originally discovered the medication in 1989 while looking for a treatment for heart-related chest pain.[9] It was approved for medical use in read full article the United States and in the European Union in 1998.[5][8][9][10] In 2017, it was the 217th-most commonly prescribed medication in the United States, with more than two million homesite prescriptions.[11][12] That same year, it also became available as a generic medication after final patents by Pfizer expired.[13] In the United Kingdom, it is available over the counter.[14] Most of the Active Pharmaceutical Ingredient (API) in Sildenafil, Sildenafil citrate, is produced in Pfizer's Ringaskiddy complex, County Cork, which is Pfizer's largest production facility outside of the United States.[15]